­
­
­
­

Inventi Impact: Dermatology

Articles

  • Inventi:hdr/22740/17
    Histological and Immunohistochemical Evaluation of the Efficacy of a New Cosmetic Formulation in\nthe Treatment of Skin Photoaging
    01-Jan-1970 Research 2017 : July - September
    M T Truchuelo, N Jimenez, L Miguel-Gomez, A Hermosa, N Sanchez-Neila, J Cuevas

    Objective. Mechanism of action of cosmetic products is not often studied. The aim of this study is to determine the histological,\nimmunohistochemical, and clinical changes of a new cosmetic formulation. Methods. Prospective, single-blind, patient-controlled,\nrandomized study in 10 volunteers with mild to moderate skin photoaging on the back of their hands. The product was applied\non one hand and a standard cream on the other hand, twice a day for three months. Standardized photographs were taken on\nbasal (T0) and final visit (T1) and skin biopsies were performed. Changes on histological and immunohistochemical markers were\nstudied. Subjective clinical changes were determined. Results. After treatment, a 26.3% improvement on epidermal thickness was\ndetected and a significant increase on collagens I and III, elastin, and fibronectin fibers was achieved (

    How to Cite this Article
    CC Compliant Citation: M. T. Truchuelo, N. Jiménez, L. Miguel-\nGomez, A. Hermosa, N. Sánchez-Neila, and J. Cuevas, â??Histological\nand Immunohistochemical Evaluation of the Efficacy of a New\nCosmetic Formulation in the Treatment of Skin Photoaging,â?\nDermatology Research and Practice, vol. 2017, Article ID\n8407247, 10 pages, 2017. doi:10.1155/2017/8407247, http://\ncreativecommons.org/licenses/by/4.0/.
    Download Full Text